Plants in the mainly tropical Dogbane Family (Apocynaceae) are annual or perennial herbs, shrubs, trees, and vines with milky sap, simple leaves, bisexual flowers with 5 sepals, 5 stamens, 2 pistils, and 5 petals joined at the base (the corollas are sometimes 4-lobed), and fruit in the form of dry, paired follicles filled with numerous seeds. The flower bud corollas are rotated or twisted so that the flower petals open in an overlapping pinwheel.

Listed below are some of the southeastern Arizona plants in this family.